The Diurnal Pattern of Salivary Flow in Normal and Depressed Patients

Publisher Website
Google Scholar
Abstract
Salivary flow was measured at two-hourly intervals throughout the day and night in normal controls and in 20 female patients complaining of depression accompanied by diurnal variation in mood and early morning waking. A diurnal rhythm in salivary flow was demonstrated for the first time in normal subjects. In depressed patients the results showed significantly diminished flow throughout the 24 hours compared to controls, and a complete reversal of normal diurnal rhythm. There was a gradual recovery in flow and return to normal rhythm during treatment with E.C.T. The diagnostic value and other implications of the test are discussed.