STREPTOMYCIN, SUPPRESSION, AND THE CODE
- 1 May 1964
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 51 (5) , 883-890
- https://doi.org/10.1073/pnas.51.5.883
Abstract
Streptomycin and related antibiotics cause extensive and specific alterations in the coding properties of synthetic polynucleotides in vitro. Streptomycin-resistant ribosomes are resistant only to the shift in the code induced by streptomycin. These findings provide evidence that the ribosomes control the accuracy of the reading and may have a role in suppression.Keywords
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