Towards a Synthesis of Epothilone A: Rapid Assembly of the C1-C6 and C7-C12 Fragments
- 1 July 1997
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1997 (7) , 824-826
- https://doi.org/10.1055/s-1997-5757
Abstract
A very short 4-step synthesis of the C1-C6 and C7-C12 fragments 3 and 4 of epothilone A (1a), starting from bornane-10,2-sultam 5, was achieved in 77% and 56% overall yield respectively.Keywords
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