CORPORA LUTEA ATRETICA IN OVARIAN GRAFTS

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Abstract
Detection of ovulation or processes resembling ovulation in ovarian grafts is regularly used to demonstrate ovulatory discharge of gonadotrophins. However, corpora lutea atretica (CLA), i.e. corpora lutea with entrapped ova, are often found (Noyes, Yamate & Clewe, 1958; Moll & Zeilmaker, 1966; Quinn, 1966). Since CLA occur not only in grafts (Deanesley, 1956; Jones & Krohn, 1960) but also in ovaries in situ (Jones & Krohn, 1961), especially after an inadequate ovulatory stimulus (Rowlands, 1944), they may reflect both abnormal responsiveness of the tissue after grafting and abnormal discharge of gonadotrophins. Therefore, the occurrence of CLA in ovarian grafts functioning under normal hormonal control was studied. In a first experiment neonatal rats were ovariectomized unilaterally (15 rats) or bilaterally (12 rats) and received one ovarian autograft under the left kidney capsule. Normal (19) and unilaterally ovariectomized rats (16) served as controls. The rats were killed during the first, fifth or

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