CHANGES IN THE NUMBER OF MOUSE THYROTROPES FOLLOWING RADIOTHYROIDECTOMY
- 1 July 1966
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 52 (3) , 391-398
- https://doi.org/10.1530/acta.0.0520391
Abstract
Mouse thyrotropes were identified as alcian blue positive cells. Their frequency was found to drop from 0.87% in normal animals to 0.11% in animals radiothyroidectomized since 30 days. This decrease is only apparent since a pulse feeding of thyroxine to radiothyroidectomized mice caused a regranulation of the TSH [thyroid stimulating hormone] depleted cells and revealed as many as 2.93% alcian blue positive cells. Since no mitoses were found to account for the increased number of thyrotropes, it is likely that radiothyroidectomy "mobilized" other existing pituitary cells, possibly chromophobes.This publication has 10 references indexed in Scilit:
- Number and distribution of thyrotropic cells in the mouse pituitary glandThe Anatomical Record, 1965
- THYROTROPHIC HORMONE IN THE PLASMA AND ANTERIOR PITUITARY OF THE THYROIDECTOMIZED RATJournal of Endocrinology, 1964
- The Pituitary Changes in Mice Undergoing Thyroid HyperplasiaBritish Journal of Cancer, 1961
- CHANGES IN THE THYROIDECTOMY CELLS OF THE RAT PITUITARY UNDER THE INFLUENCE OF LARGE DOSES OF TRIIODOTHYRONINE1Endocrinology, 1961
- CHANGES IN THE BASOPHIL CELLS OF THE RAT PITUITARY AFTER THYROIDECTOMYJournal of Endocrinology, 1956
- THE MORPHOGENESIS OF PITUITARY TUMORS INDUCED BY RADIOTHYROIDECTOMY IN THE MOUSE AND THE EFFECTS OF THEIR TRANSPLANTATION ON THE PITUITARY BODY OF THE HOST1954
- Hormone-Secreting Transplantable Neoplasms of the Pituitary Induced by I131.Experimental Biology and Medicine, 1951
- ON THE NATURE OF THE HYPERTROPHIED PITUITARY GLAND INDUCED IN THE MOUSE BY I131INJECTIONS, AND THE MECHANISM OF ITS DEVELOPMENTEndocrinology, 1951
- Tumorous Growths in the Pituitary and Trachea Following Radio toxic Dosages of I131.Experimental Biology and Medicine, 1949
- THE EFFECT OF THYROXIN INJECTIONS ON THE THYROTROPHIN CONTENT OF THE ANTERIOR PITUITARY OF THE MALE ALBINO MOUSE1Endocrinology, 1944