GENE EXPRESSION IN DIFFERENTIATED CELLS
Open Access
- 1 January 1963
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 49 (1) , 53-60
- https://doi.org/10.1073/pnas.49.1.53
Abstract
Actinomycin D was used to study gene control over specific cellular activities in an established cultured cell line preserving a differentiated biosynthetic function in vitro. It was found that the specific biosynthesis characteristic of these cells was subject to immediate genomlc control, while, by contrast, specific activity of a mitochondrial enzyme was not affected by actinomycin treatment.Keywords
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