Synthesis ofN,N′-Diaryldipeptide Amides by Multi-Component Condensation Utilizing Potassium Isocyanoacetate
- 1 January 1994
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1994 (07) , 672-674
- https://doi.org/10.1055/s-1994-25541
Abstract
The reaction between ketones 1, amine hydrochlorides 2, and potassium isocyanoacetate (3) affords a series of dipeptide derivatives 5. The structure of compounds 5 is in agreement with their spectral data and is confirmed by means of X-ray analysis of 5a.Keywords
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