Pharmacokinetics and Pharmacodynamics of Zileuton after Oral Administration of Single and Multiple Dose Regimens of Zileuton 600mg in Healthy Volunteers
- 1 January 1995
- journal article
- clinical trial
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 29 (2) , 22-33
- https://doi.org/10.2165/00003088-199500292-00005
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Determination of a New 5-Lipoxygenase Inhibitor, Zileuton, and its Inactive N-Dehydroxylated Metabolite in Plasma by High Performance Liquid ChromatographyClinical Pharmacokinetics, 1995
- The Effect of Inhibition of 5-Lipoxygenase by Zileuton in Mild-to-Moderate AsthmaAnnals of Internal Medicine, 1993
- The discovery and development of zileuton: An orally active 5-lipoxygenase inhibitorInternational Journal of Immunopharmacology, 1992
- Glucuronidation of zileuton (A-64077) by human hepatic microsomes.1992
- Phase II study of the safety and efficacy of a 5-lipoxygenase inhibitor in patients with ulcerative colitis.1992
- 1 5-Lipoxygenase Inhibitors and their Anti-inflammatory ActivitiesProgress in Medicinal Chemistry, 1992
- Effect of Zileuton (A-64077) on the 5-lipoxygenase activity of human whole bloodex vivoInflammation Research, 1991
- 5-lipoxygenase inhibitory activity of zileuton.1991
- The Effects of a 5-Lipoxygenase Inhibitor on Asthma Induced by Cold, Dry AirNew England Journal of Medicine, 1990
- Leukotrienes and Lipoxins: Structures, Biosynthesis, and Biological EffectsScience, 1987