Vip Increases in Nasal Blood During Stimulation of the Vidian Nerve

Abstract
In chronically sympathetomized cats Vidian nerve stimulation evoked vasodilatation concomitant with an increase of VIP [vasoactive intestinal polypeptide] concentration in venous plasma effluent from the nasal mucosa. The VIP increase and the vasodilation was not affected by atropine administration, but abolished by hexamethonium. Neuronal VIP may be the mediator of the atropine-resistant vasodilation.