Discharge of intracellular amino acid pools
- 1 March 1980
- journal article
- Published by Wiley in Cell Biology International Reports
- Vol. 4 (3) , 295-301
- https://doi.org/10.1016/0309-1651(80)90062-4
Abstract
Amino acid discharge from a labelled intracellular acid-soluble (acid-extractable) pool occurs as a negative exponential, which is not affected by pool size or concentration of amino acid in the chase medium. Simple negative exponentials were observed over the range 7-37 degrees C, but the slopes were dependent on temperature. Discharge kinetics do not appear to be mirror images of the kinetics of uptake into the acid-extractable pool. The results lend particular support to the efferent limb of the cyclical perfusion model of amino acid utilisation proposed by Wheatley and Inglis (1980).Keywords
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