Characterization of Monoclonal Antibody Specific for Human Alpha Interferon
- 1 January 1982
- journal article
- research article
- Published by Mary Ann Liebert Inc in Hybridoma
- Vol. 1 (3) , 313-322
- https://doi.org/10.1089/hyb.1.1982.1.313
Abstract
A mouse hybridoma cell line has been isolated, which secretes a monoclonal antibody specific of human leukocyte (α) interferon. The antibody secreted by the hybridoma belongs to the IgG1 class. It neutralizes biological activities (cellular and antiviral) of α interferon. Mass production of the antibody in ascitic fluid has been obtained. A convenient method of purification of the IgG from the ascitic fluid on DEAE-Trisacry1 M is described.This publication has 15 references indexed in Scilit:
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