Intestinal Goblet Cell Differentiation in Nippostrongylus-Infected Rats after Transfer of Fractionated Thoracic Duct Lymphocytes
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 59 (3) , 281-285
- https://doi.org/10.1159/000232271
Abstract
Adoptive immunization of Nippostrongylus-infected rats augmented goblet cell differentiation in the intestinal epithelium. After fractionation of immune thoracic duct lymphocytes (TDL), cells lacking surface immunoglobulin (sIg––) were the most potent stimulators of goblet cell differentiation. Moreover, TDL drained from rats harbouring a primary infection were more effective than TDL from hyperimmune rats.Keywords
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