Thyroid-Stimulating Immunoglobulins and the Control of Thyroid Function

1 September 1976

journal article
research article
Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism

Vol. 43 (3) , 550-556
https://doi.org/10.1210/jcem-43-3-550

Abstract

Triiodothyronine (T₃) suppression and thyrotropin-releasing hormone (TRH) tests were used to study thyroid function in 50 patients with thyroid disease. The results of the thyroid function tests were compared with the levels of serum thyroid-stimulating immunoglobulins (TSI) measured by a radio-receptor assay. In euthyroid and hyperthyroid patients, the presence of TSI corresponded with the absence of TSH control of thyroid function. However, in two hypothyroid patients with serum TSI levels readily detectable in the receptor assay, T₃ suppression and TRH tests indicated that thyroid function was under TSH control.

Keywords

This publication has 1 reference indexed in Scilit:

Suppressibility of Thyroid Function Despite High Levels of Long-Acting Thyroid Stimulator
Annals of Internal Medicine, 1972