Structural and conformational analysis by 1H NMR and 13C NMR of a new angiotensin I converting enzyme inhibitor, the tert‐butylamine salt of (2S)‐2‐[(1S)‐1‐carbethoxybutylamino]‐1‐oxopropyl‐(2S, 3aS, 7aS) perhydroindole‐2‐carboxylic acid (perindopril)
- 1 April 1988
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Chemistry
- Vol. 26 (4) , 296-302
- https://doi.org/10.1002/mrc.1260260405
Abstract
Perindopril, a potent inhibitor of angiotensin I converting enzyme, was studied by 1H NMR and 13C NMR in various solvents and at various temperatures. The cis and trans conformations of the amide bond were assigned. The conformations of the perhydroindole skeleton rings were studied by 1H NMR.Keywords
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