Probing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE
- 30 June 2009
- journal article
- Published by Elsevier in Molecular and Biochemical Parasitology
- Vol. 165 (2) , 122-131
- https://doi.org/10.1016/j.molbiopara.2009.01.011
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Extensive Genetic Diversity in the Plasmodium falciparum Na + /H + Exchanger 1 Transporter Protein Implicated in Quinine ResistanceAntimicrobial Agents and Chemotherapy, 2007
- Plasmodium falciparum Na+/H+ exchanger activity and quinine resistanceMolecular and Biochemical Parasitology, 2007
- Transporters involved in resistance to antimalarial drugsTrends in Pharmacological Sciences, 2006
- Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoformsMolecular and Biochemical Parasitology, 2006
- Decreasingpfmdr1Copy Number inPlasmodium falciparumMalaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and ArtemisininThe Journal of Infectious Diseases, 2006
- pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparumMolecular Microbiology, 2005
- Chloroquine Resistance Modulated in Vitro by Expression Levels of the Plasmodium falciparum Chloroquine Resistance TransporterJournal of Biological Chemistry, 2003
- Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extensionPublished by Elsevier ,2003
- Fluorescent molecular probes III. 2′,7′-Bis-(3-carboxypropyl)-5-(and-6)-carboxyfluorescein (BCPCF): a new polar dual-excitation and dual-emission pH indicator with a pKa of 7.0Bioorganic & Medicinal Chemistry Letters, 1997
- Reversal of Chloroquine Resistance in Plasmodium falciparum by VerapamilScience, 1987