Affordable diagnosis of human immunodeficiency virus infection in infants by p24 antigen detection
- 1 February 2004
- journal article
- Published by Wolters Kluwer Health in The Pediatric Infectious Disease Journal
- Vol. 23 (2) , 173-176
- https://doi.org/10.1097/01.inf.0000109332.83246.1a
Abstract
The expense of PCR testing limits diagnosis of HIV infection in infancy in low resource settings. The ultrasensitive p24 antigen assay has been proposed as an accurate substitute; however, its ability to detect different HIV viral subtypes remains to be determined. A sensitivity of 98.1% and specificity of 98.7% was obtained testing 203 samples from 24 HIV-infected and 66 uninfected infants born to HIV subtype C-infected women.Keywords
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