Mass Spectral Analysis in Proteomics
- 9 June 2004
- journal article
- review article
- Published by Annual Reviews in Annual Review of Biophysics
- Vol. 33 (1) , 297-316
- https://doi.org/10.1146/annurev.biophys.33.111502.082538
Abstract
▪ Abstract Mass spectrometry provides key tools for the analysis of proteins. New types of mass spectrometers that provide enhanced capability to discover protein identities and perform improved proteomic experiments are discussed. Handling the complex mixtures of peptides and proteins generated from protein complexes and whole cells requires multidimensional separations; several forms of separation are discussed. Applications of mass spectrometry–based approaches for contemporary proteomic analyses are described.Keywords
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