The Stability of Deoxyribonucleic Acid Solutions Under High Pressure.

Abstract
Exposure of DNA to a pressure of 10 000 atm does not cause denaturation. In the pressure range of 1[long dash]2700 atm, a stabilizing effect against heat denaturation was found, the denaturation temperature being[image]6[degree]C higher at 2700 atm than at 1 atm. In parallel with the denaturation temperature, the optimum temperature for renaturation of denatured DNA is raised.