Asymmetric Syntheses Based on Hexahydro-4,4,7-Trimethyl-1,3-Benzoxathians
- 1 June 1985
- journal article
- research article
- Published by Taylor & Francis in Phosphorus and Sulfur and the Related Elements
- Vol. 24 (1-2) , 73-95
- https://doi.org/10.1080/03086648508073397
Abstract
Earlier work concerned with a highly stereoselective asymmetric synthesis based on a 1,3-oxathiane as the ciral auxiliary reagent is reviewed and recent applications to the synthesis of the four stereoisomers of malyngolide, of (R)-(+)-γ-caprolactone (a pheromone of the Trogoderma glabrum beetle) and of (S)-(+)-mevalolactone are presented. The mechanism underlying this asymmetric synthesis is discussed briefly.Keywords
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