A Novel Synthesis of 4(3H)-Pteridinone Derivatives via Intermolecular Aza-Wittig Reaction
- 1 January 1994
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1994 (07) , 555-556
- https://doi.org/10.1055/s-1994-22927
Abstract
Aza-Wittig reaction of iminophosphorane 2, derived from methyl 3-aminopyrazine-2-carboxylate 1, with isocyanates followed by addition of alcohol or amine provided a novel synthetic route to 2,3-disubstituted 4(3H)-pteridinones.Keywords
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