An Outbreak of Q Fever in Sokol, Yugoslavia, August 1950

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Abstract
Complement-fixation tests with Q fever antigen were performed on the acute and convalescent phase sera of 9 individuals from an epidemic characterized by fever, headache, and malaise in the village of Sokol, Bosnia, Yugoslavia, in Aug., 1950. All 9 individuals showed a marked rise in Q fever antibody titers in their convalescent serum specimens confirming the clinical impression that this was an outbreak of Q fever. Nine individuals giving a history and serologic evidence of past infection with epidemic typhus developed what appeared to be typical Q fever. Apparently, past infection with epidemic typhus offers very little or no protection against Q fever. In 9 individuals with a positive history and serologic evidence of past infection with epidemic typhus, a subsequent Q fever infection caused no anamnestic rise of the residual epidemic typhus antibody titers.
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