Reversible selective β2‐adrenoceptor agonist‐induced myopathy

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Abstract
Sir, Salbutamol and formoterol, two β2‐adrenergic agonists, are commonly prescribed in bronchospasm. Headache, shaking, palpitation and skin rash are the most common side‐effects related to these compounds. Muscle cramps have also been reported but are usually mild and do not necessitate stoppage of the treatment. We report a patient with clinical, reversible β2‐adrenoceptor agonist myopathy. The myopathy was demonstrated electrically and histologically. He had received a well‐documented high cumulative dose of β2‐adrenoceptor agonists, and in whom no other drug could be implicated.