Conformation of zearalenone in solution: A vicinal coupling constant and molecular mechanics study

Abstract
Vicinal coupling constants of stereochemical significance were obtained in four solvents for zearalenone and specifically deuteriated zearalenone. Comparison with values calculated for several conformations using molecular mechanics calculations indicates that zearalenone exists in a single conformation in solution. The solvent dependence observed for the H‐9′ and H‐10′ signals cannot be attributed to a conformational equilibrium.