The Antimelanoma Immunocytokine scFvMEL/TNF Shows Reduced Toxicity and Potent Antitumor Activity against Human Tumor Xenografts

This publication has 56 references indexed in Scilit:

• The immunocytokine scFv23/TNF sensitizes HER-2/neu–overexpressing SKBR-3 cells to tumor necrosis factor (TNF) via up-regulation of TNF receptor-1
  Molecular Cancer Therapeutics, 2005
• Coupling Tumor Necrosis Factor-α with αV Integrin Ligands Improves Its Antineoplastic Activity
  Cancer Research, 2004
• Human tumor necrosis factor-α mutant RGD-V29 (F4614) shows potent antitumor activity and reduced toxicity against human tumor xenografted nude mice
  Cancer Letters, 2000
• Novel muteins of human tumor necrosis factor with potent antitumor activity and less lethal toxicity in mice
  International Journal of Cancer, 1995
• Efficacy of tnf-α gene-transduced tumor cells in treatment of establishedin vivo tumor
  International Journal of Cancer, 1995
• A genetically engineered single-chain FVTNF molecule possesses the anti-tumor immunoreactivity of FV as well as the cytotoxic activity of tumor necrosis factor
  Molecular Immunology, 1995
• Targeting of tumor necrosis factor to tumor cells: secretion by myeloma cells of a genetically engineered antibody-tumor necrosis factor hybrid molecule
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1991
• Cytostatic and Cytotoxic Effects of Recombinant Tumor Necrosis Factor-α on Sensitive Human Melanoma Cells In Vitro May Result in Selection of Cells with Enhanced Markers of Malignancy
  Journal of Investigative Dermatology, 1990
• Single-Chain Antigen-Binding Proteins
  Science, 1988
• Analysis of the NIH Workshop Monoclonal Antibodies to Human Melanoma Antigens
  Hybridoma, 1982