EFFECT OF LARYNGOSCOPY AND INTUBATION ON PLASMA CATECHOLAMINE LEVELS DURING INTRAVENOUS INDUCTION OF ANAESTHESIA

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Abstract
The effect of laryngoscopy and the introduction of a bronchography tube on blood pressure, heart rate, rhythm and plasma catecholamines was studied in 30 patients during three different modes of anaesthesia induction (thiopentone 5 mg/kg followed by suxamethonium 1 mg/kg, propanidid 7 mg/kg followed by suxamethonium 0.2 mg/kg and propanidid 10 mg/kg). Laryngoscopy and intubation caused an increase in systolic blood pressure in all groups, although the increase was not statistically significant after propanidid alone. Levels of total plasma catecholamines, measured during and two minutes after laryngoscopy, remained unchanged in all groups. The preanaes-thetic content of noradrenaline as a percentage of total catecholamines was higher in those patients who developed a more marked increase in blood pressure during laryngoscopy and intubation.

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