Age and Infectivity of the Filariform Larvae of the Rat Nematode Nippostrongylus brasiliensis (Travassos, 1914)

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Abstract
Filariform larvae of N. brasiliensis that varied in chronological age from 3 to 111 days were studied with respect to their infectivity for laboratory rats. Infectivity was high and showed little change for larvae that ranged from 3 days up to about 4 weeks in age. Beyond this time there was some marked variation in rate, but ultimately larval infectivity decreased as larval age increased. Some of the larvae that were 111 days in age were still capable of developing to maturity in the rat host, but the percentage development was very small. Tests made with larvae raised in the same culture dish showed the same general trend as that obtained with larvae reared from different stock infections or in different culture dishes.
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