Rapid diagnosis of Legionella pneumophila serogroup 1 infection with the Binax enzyme immunoassay urinary antigen test
- 1 April 1997
- journal article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 35 (4) , 954-6
- https://doi.org/10.1128/jcm.35.4.954-956.1997
Abstract
The Binax legionella urinary antigen (LUA) enzyme immunoassay (Binax, Portland, Maine) was evaluated in 159 patients with suspected or proven legionellosis and 209 controls. A positive LUA test was found in 37% of patients with suspected legionellosis overall and in 83% of those with proven Legionella pneumophila serogroup 1 infection. The sensitivity of the LUA test was significantly greater than that of the direct fluorescent-antigen test (83 versus 42%; P < 0.0001) but not significantly different from that of culture (85%) or serology (91%); specificity was at least 99.5%.Keywords
This publication has 9 references indexed in Scilit:
- Characterisation of Legionella pneumophila antigen in urine of guinea pigs and humans with Legionnaires' diseaseJournal of Infection, 1995
- Detection ofLegionella DNA in human and guinea pig urine samples by the polymerase chain reactionEuropean Journal of Clinical Microbiology & Infectious Diseases, 1995
- Microbiological aspects of an outbreak of Legionnaires’ disease in South Western SydneyPathology, 1994
- A prospective hospital study of the aetiology of community‐acquired pneumoniaThe Medical Journal of Australia, 1989
- Antigen detection for the rapid diagnosis of mycoplasma and legionella pneumoniaDiagnostic Microbiology and Infectious Disease, 1986
- Recent Advances in the Diagnosis of Serogroup 1 L. pneumophila Pneumonia by Detection of Urinary AntigenZentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale. A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1983
- Detection of Legionella pneumonophila antigen in urine by enzyme-linked immunospecific assayJournal of Clinical Microbiology, 1979
- Legionnaires' Disease Antigen Detected by Enzyme-Linked Immunosorbent AssayAnnals of Internal Medicine, 1979
- Dust Control in Measles WardsBMJ, 1947