Mechanistic Basis for Suicide Inactivation of Porphobilinogen Synthase by 4,7-Dioxosebacic Acid, an Inhibitor That Shows Dramatic Species Selectivity
- 16 June 2001
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 40 (28) , 8227-8236
- https://doi.org/10.1021/bi010656k
Abstract
No abstract availableKeywords
This publication has 12 references indexed in Scilit:
- The Molecular Mechanism of Lead Inhibition of Human Porphobilinogen SynthaseJournal of Biological Chemistry, 2001
- An Artificial Gene for Human Porphobilinogen Synthase Allows Comparison of an Allelic Variation Implicated in Susceptibility to Lead PoisoningPublished by Elsevier ,2000
- High resolution crystal structure of a Mg2+-dependent porphobilinogen synthaseJournal of Molecular Biology, 1999
- X-ray Structure of 5-Aminolevulinic Acid Dehydratase from Escherichia coli Complexed with the Inhibitor Levulinic Acid at 2.0 Å ResolutionBiochemistry, 1999
- Heme Synthesizing Enzymes ofPlasmodium knowlesi:A Simian Malarial ParasiteExperimental Parasitology, 1998
- Metal coordination of several divalent cations: Mg2+, Ca2+, Be2+, and Zn2+Acta Crystallographica Section A Foundations of Crystallography, 1996
- Bradyrhizobium japonicum Porphobilinogen Synthase Uses Two Mg(II) and Monovalent CationsPublished by Elsevier ,1996
- Estimating KI values for tight binding inhibitors from dose-response plotsBioorganic & Medicinal Chemistry Letters, 1995
- AMoRe: an automated package for molecular replacementActa Crystallographica Section A Foundations of Crystallography, 1994
- δ‐Aminolevulinic Acid Dehydratase Isozymes and Lead ToxicityaAnnals of the New York Academy of Sciences, 1987