Effect of the Hypnotic Flurazepam on the Sleep of Pentazocine and Heroin Addicts during Withdrawal
- 1 January 1983
- journal article
- Published by Taylor & Francis in International Journal of the Addictions
- Vol. 18 (3) , 407-418
- https://doi.org/10.3109/10826088309039357
Abstract
Fourteen male heroin addicts being detoxified on methadone and 14 male pentazocine addicts being detoxified drug-free were observed over a 24-hour period for 2 weeks in their sleeping patterns to assess the effects of flurazepam upon sleep during withdrawal. Results of objective and subjective measures find that flurazepam use is associated with more objective nighttime arousals and less total sleep for the heroin group compared to the pentazocine group. Heroin patients felt they had a poorer quality of sleep and took flurazepam more frequently than did the pentazocine patients. Heroin patients' assessments of their sleep and number of arousals correlated poorly with observations.Keywords
This publication has 7 references indexed in Scilit:
- Acute heroin abstinence in man: I. Changes in behavior and sleepDrug and Alcohol Dependence, 1980
- Opioid Effects on Computer-Derived Sleep and EEG Parameters in Nondependent Human AddictsSleep, 1979
- Brain Specific Benzodiazepine ReceptorsThe British Journal of Psychiatry, 1978
- The Opiate ReceptorsAnnual Review of Pharmacology and Toxicology, 1978
- Behavioral and Social Effects of Heroin Self-Administration and WithdrawalArchives of General Psychiatry, 1976
- Human sleep and EEG through a cycle of methadone dependenceElectroencephalography and Clinical Neurophysiology, 1975
- II. All-night EEG Studies of Chloral Hydrate, Flurazepam, and MethaqualoneArchives of General Psychiatry, 1970