Abstract
In acute scurvy, a 25% decrease in albumin, 50% increase in fibrinogen and 10% increase in [alpha]-glubolin were found in guinea pig plasma, although total protein content was unchanged. In chronic scurvy there was a 15% decrease from normal in albumin, a 70% increase in fibrinogen, a 40% increase in gamma-globulin, but no change in [alpha]-globulin. Electrophoretic mobility on paper of plasma proteins from normal and scorbutic guinea pigs did not differ.

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