The Unique NH2-terminally Deleted (ΔN) Residues, the PXXP Motif, and the PPXY Motif Are Required for the Transcriptional Activity of the ΔN Variant of p63
Open Access
- 1 February 2006
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 281 (5) , 2533-2542
- https://doi.org/10.1074/jbc.m507964200
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Characterization of p73 functional domains necessary for transactivation and growth suppressionOncogene, 2003
- ΔNp63α functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytesOncogene, 2003
- The Activation Domains, the Proline-rich Domain, and the C-terminal Basic Domain in p53 Are Necessary for Acetylation of Histones on the Proximal p21 Promoter and Interaction with p300/CREB-binding ProteinJournal of Biological Chemistry, 2003
- The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosisOncogene, 2002
- p63 and p73 are required for p53-dependent apoptosis in response to DNA damageNature, 2002
- TP63 gene mutation in ADULT syndromeEuropean Journal of Human Genetics, 2001
- Physical Interaction with Yes-associated Protein Enhances p73 Transcriptional ActivityJournal of Biological Chemistry, 2001
- Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activityOncogene, 1999
- Modular binding domains in signal transduction proteinsCell, 1995
- Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein.Genes & Development, 1994