The Synthetic Utility of Heteroaromatic Azido Compounds. III. Preparation of Some Furo-, Thieno- and Selenolo[3,2-b]pyrroles.
- 1 January 1976
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 30b (5) , 391-396
- https://doi.org/10.3891/acta.chem.scand.30b-0391
Abstract
Some 3-azido-2-vinyl derivatives of furan, thiophene and selenophene were used for preparation of [3,2-b]-fused pyrrole systems by thermal decomposition. One of the resulting derivatives, 5-nitroacetylthieno-[3,2-b]pyrrole could be transformed to the corresponding unsubstituted thieno[3,2-b]pyrrole by alkaline treatment at high temperature. Attempts to obtain the unsubstituted furo- and selenolo-fused systems by this method failed. The 1H and 13C NMR parameters for the thieno[3,2-b]pyrrole are presented. [These compounds may be important as potential drugs or drug intermediates.].This publication has 0 references indexed in Scilit: