Studies on Some Actions of Sulphated Polysaccharides on Arteriosclerosis (II) : INHIBISION OF EXPERIMENTAL ATHEROSCLEROSIS WITH DEXTRAN SULPHATE
- 1 January 1961
- journal article
- Published by Japanese Circulation Society in Japanese Circulation Journal
- Vol. 25 (6) , 570-573
- https://doi.org/10.1253/jcj.25.570
Abstract
We reported previously chemical and physical properties of the dextran sulphate which we synthesized newly. Intravenous administration of this preparation inhibited the atherosclerosis induced with lanolin feeding in rabbits and depressed hypercholesterolemia. The fat content and weight of spleen were slightly heavier than that of control animals. The metachromatic substances in atheroma and walls of aortae were not different between dextran sulphate treated and control animals.Keywords
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