13C Nuclear Magnetic Resonance and Circular Dichroism Studies of the Tuftsin Conformation in Water
- 1 November 1980
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 112 (2) , 339-343
- https://doi.org/10.1111/j.1432-1033.1980.tb07210.x
Abstract
13C-NMR and circular dichroic (CD) spectra of tuftsin and its analogues are discussed in connection with the hypothesis that the .beta.-turn is the biologically active conformation of tuftsin. The changes in CD spectra evoked by an increase in pH are interpreted as a demonstration of the increasing amount of .beta.-turn conformers in solution. Configurational changes in successive residues of tuftsin showed that residues 2 and 3 of the peptide chain are important for the tuftsin conformation.This publication has 16 references indexed in Scilit:
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