Effect of High Sodium Intake on the Response of the Rat Adrenal to Angiotensin II
- 1 February 1969
- journal article
- other
- Published by The Endocrine Society in Endocrinology
- Vol. 84 (2) , 462-463
- https://doi.org/10.1210/endo-84-2-462
Abstract
The adrenal glands of intact male rats fed a high sodium diet have a normal content of corticosterone and a low content of aldosterone. A low sodium diet is associated with a reduction of corticosterone and a marked increase in aldosterone. Chronic angiotensin treatment which has been previously shown to stimulate secretion of aldosterone and corticosterone is ineffective in the presence of a high sodium diet. Dietary sodium plays a significant role in the response of the rat adrenal to angiotensin. (Endocrinology84: 462, 1969)Keywords
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