A STUDY OF ALPHA2-MACROGLOBULIN HOMOLOGUES OF VARIOUS SPECIES

  • 1 January 1965
    • journal article
    • research article
    • Vol. 8  (1) , 55-+
Abstract
The antigenic relationships between the [alpha]2-macroglobulin homologues of a large number of species (predominantly mammalian) have been studied by the gel diffusion pre-cipitin technique using a specific antiserum to human [alpha]2-macroglobulin raised in a rabbit. This antiserum has been absorbed with eleven different mammalian sera and the ability of the absorbed samples to cross-react with all these sera has again been tested. From these results an attempt has been made to calculate the minimum number of antigenic determinants on each [alpha]2-macroglobulin homologue recognized by this rabbit antiserum.