USE OF BUMETANIDE, A POTENT DIURETIC, TO OBTAIN URINARY SAMPLES FOR DOPE TESTING IN HORSES

  • 1 January 1976
    • journal article
    • research article
    • Vol. 37  (11) , 1257-1260
Abstract
Using bumetanide it was possible to obtain urinary samples for dope [phenobarbital, d-amphetamine] testing of trotters within the 1st h after the race. The drug was injected i.v. at a dose level of 10 .mu.g/kg during the cold season of the year, but on warm days, a dose of 20 .mu.g/kg was more reliable. These doses did not produce any side-effects and did not interfere with the detection of doping drugs, since bumetanide is not metabolized to a detectable degree and the unchanged drug appears only in extracts from acidic urine. By enhancing the clearance of drugs used for doping, bumetanide provides favorable conditions for detection of such drugs.

This publication has 0 references indexed in Scilit: