Mutation of Pseudomonas aeruginosa to piperadillin resistance mediated by β-lactamase production
- 1 June 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 15 (6) , 665-670
- https://doi.org/10.1093/jac/15.6.665
Abstract
Piperacillin-resistant mutants were detected in each of ten strains of Pseudomonas aeruginosa. The resistance was associated with constitutive production by the strains of high levels of β-lactamase which was similar in character to the induced chromosomal Id β-lactamase of the parent strains. This type of mutation to piperacillin-resistance occurred at a low frequency. The β-lactamase production and piperacillin-resistance were stable on repeated subculture and prolonged storage of the strains.Keywords
This publication has 0 references indexed in Scilit: