RK mutatest variations for rapid independent determination of toxicity and mutagenicity

1 May 1988

journal article
research article
Published by Wiley in Environmental Toxicology and Water Quality

Vol. 3 (3) , 287-302
https://doi.org/10.1002/tox.2540030305

Abstract

The RK mutatest is a recently developed, forward, short‐term, bacterial genetic test system for quantitation of mutagenic activity and toxicity. Rapid quantitative, semi‐quantitative, and qualitative variations of the standard RK mutatest protocol were developed and tested using reference genotoxic agents. Several of the reported mutatest modifications considerably reduced assay time, and would be useful for a quick first‐stage evaluation of the biological damaging effect of environmental substances.

Keywords

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