EFFECTS OF DIET DURING PREGNANCY ON DEVELOPMENT OF RICKETS IN THE OFFSPRING

Abstract
Rickets has been shown by many investigators, including Dunham, 1 DeBuys, 2 Park 3 and Eliot, 4 to be a disease that begins during the first four months of life. This early development emphasizes the importance of a possible prenatal influence on the disease. Hess and Weinstock, 5 using the modern methods of study by roentgenograms, found that the administration of cod liver oil to pregnant mothers did not prevent rickets in their infants. Practically all the other experimental evidence on the rôle of maternal nutrition in its relation to the occurrence of rickets in the offspring has been obtained by studies of rats. Byfield and Daniels, 6 and Korenchevsky and Carr 7 obtained some effect in prevention. The usual opinion is expressed by Hess and Weinstock, 5 who do not believe that it is possible entirely to prevent rickets by improving the diet of the mother previous to pregnancy,

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