A model for the molecular organization of cytochrome β‐561 in chromaffin granule membranes
- 28 August 1989
- journal article
- Published by Wiley in FEBS Letters
- Vol. 254 (1-2) , 74-78
- https://doi.org/10.1016/0014-5793(89)81012-9
Abstract
The CD spectrum of reduced cytochrome (cyt.) β-561 in chromaffin granule membranes resembles that of mitochondrial cyt. β1 and indicates possible heme-heme interaction in the protein. Based on spectroscopic data and analysis of the amino acid sequence, a model of cyt. β-561 is suggested, in which the protein carries two transmembrane-localized hemes, each coordinated by two histidines. The model accounts for the presence of two different forms of cyt. β-561 in chromaffin granule membranes and provides a mechanism of transmembrane electron transfer by this hemoprotein.Keywords
This publication has 17 references indexed in Scilit:
- Improvements in a secondary structure prediction method based on a search for local sequence homologies and its use as a model building toolBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1988
- Resolution of the circular dichroism spectra of the mitochondrial cytochrome bc1 complexBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1987
- A conformational preference parameter to predict helices in integral membrane proteinsBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1986
- Bioenergetics of secretory vesiclesBiochimica et Biophysica Acta (BBA) - Reviews on Bioenergetics, 1986
- Location of haem‐binding sites in the mitochondrial cytochrome bFEBS Letters, 1984
- Unusual redox behaviour of cytochrome b-561 from bovine chromaffin granule membranesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1984
- Application of the exciton chirality method for the stereochemical assignment of remote groups. Determination of the α- or β-configuration of a 2-hydroxy-substituent in 2,17- and 2,16-dihydroxy-A-nor-5α-androstane and -estrane derivativesJournal of the Chemical Society, Perkin Transactions 2, 1982
- Oxidoreductase activities of chromaffin granule ghosts isolated from the bovine adrenal medullaBiochimica et Biophysica Acta (BBA) - Biomembranes, 1980
- Circular dichroism and resonance Raman studies of cytochrome b562 from Escherichia coliBiochemistry, 1978
- [44] Preparation and properties of reduced coenzyme Q-cytochrome c reductase (complex III of the respiratory chain)Published by Elsevier ,1967