Ex vivo fludarabine exposure inhibits graft-versus-host activity of allogeneic T cells while preserving graft-versus-leukemia effects
Open Access
- 1 October 2003
- journal article
- Published by Elsevier in Transplantation and Cellular Therapy
- Vol. 9 (10) , 616-632
- https://doi.org/10.1016/s1083-8791(03)00229-5
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- Leucyl-leucine methyl ester-treated haploidentical donor lymphocyte infusions can mediate graft-versus-leukemia activity with minimal graft-versus-host disease riskTransplantation and Cellular Therapy, 2002
- The infusion of ex vivo activated and expanded CD4+CD25+ immune regulatory cells inhibits graft-versus-host disease lethalityBlood, 2002
- Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or γ radiationBlood, 2001
- LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantationJournal of Clinical Investigation, 2001
- Lethal host-versus-graft disease and hypereosinophilia in the absence of MHC I–T-cell interactionsJournal of Clinical Investigation, 2000
- Selective depletion of major and minor histocompatibility antigen reactive T cells: towards prevention of acute graft‐versus‐host diseaseBritish Journal of Haematology, 1999
- Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease.Journal of Clinical Investigation, 1998
- HSV-TK Gene Transfer into Donor Lymphocytes for Control of Allogeneic Graft-Versus-LeukemiaScience, 1997
- Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic miceNature, 1988
- 2-Fluoro-ATP: A toxic metabolite of 9-β-D-arabinosyl-2-fluoroadenineBiochemical and Biophysical Research Communications, 1983