HEMODYNAMIC ALTERATIONS DUE TO SALMONELLA TYPHOSA ENDOTOXIN WITH SPECIAL REFERENCE TO THE CORONARY VASCULAR BED*

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Abstract
The effects of endotoxin on total peripheral resistance and on coronary vascular resistance of the beating, nonworking dog heart were studied during cardiopulmonary bypass. The administration of 0.6 mg/kg of Salmonella typhosa endotoxin directly into the coronary vascular resistance and total peripheral resistance, which appeared to be due to active vasodilatation.