Slick Recruitment to the Golgi
- 11 January 2002
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 295 (5553) , 290-291
- https://doi.org/10.1126/science.1068446
Abstract
Formation of vesicles carrying secretory proteins depends on the activity of the Golgi, the cell's central protein sorting station. In a Perspective, Bankaitis discusses new findings (Baron and Malhotra) that reveal how protein kinase D, a key molecule required for vesicle formation, is recruited to the Golgi by a lipid called diacylglycerol that is both produced and consumed within this organelle.Keywords
This publication has 9 references indexed in Scilit:
- Role of Diacylglycerol in PKD Recruitment to the TGN and Protein Transport to the Plasma MembraneScience, 2002
- Intracellular Localization of Phospholipase D1 in Mammalian CellsMolecular Biology of the Cell, 2001
- Protein Kinase D Regulates the Fission of Cell Surface Destined Transport Carriers from the Trans-Golgi NetworkCell, 2001
- Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acidNature, 1999
- Yeast Sec14p Deficient in Phosphatidylinositol Transfer Activity Is Functional In VivoPublished by Elsevier ,1999
- Gβγ-Mediated Regulation of Golgi Organization Is through the Direct Activation of Protein Kinase DCell, 1999
- Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer proteinPublished by Elsevier ,1991
- An essential role for a phospholipid transfer protein in yeast Golgi functionNature, 1990
- What is the fate of diacylglycerol produced at the Golgi apparatus?Trends in Biochemical Sciences, 1988