The Human Cyclic AMP-specific Phosphodiesterase PDE-46 (HSPDE4A4B) Expressed in Transfected COS7 Cells Occurs as Both Particulate and Cytosolic Species That Exhibit Distinct Kinetics of Inhibition by the Antidepressant Rolipram
Open Access
- 1 December 1996
- journal article
- Published by Elsevier
- Vol. 271 (49) , 31334-31344
- https://doi.org/10.1074/jbc.271.49.31334
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Alternative Splicing of cAMP-specific Phosphodiesterase mRNA TranscriptsJournal of Biological Chemistry, 1996
- Synthesis and in vitro profile of a novel series of catechol benzimidazoles. The discovery of potent, selective phosphodiesterase type IV inhibitors with greatly attenuated affinity for the [3H]rolipram binding siteBioorganic & Medicinal Chemistry Letters, 1995
- Molecular cloning and functional expression in yeast of a human cAMP‐specific phosphodiesterase subtype (PDE IV‐C)FEBS Letters, 1995
- Chromosomal localization of the human and rat genes (PDE4D and PDE4B) encoding the cAMP-specific phosphodiesterases 3 and 4Cytogenetic and Genome Research, 1995
- Molecular biology of the cyclic AMP-specific cyclic nucleotide phosphodiesterases: A diverse family of regulatory enzymesCellular Signalling, 1994
- [3H]Rolipram binding and phosphodiesterase activity in neuroblastoma N18TG-2 and glioma C6Bu-1Neuroscience Letters, 1994
- Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.The Journal of cell biology, 1993
- Primary sequence of cyclic nucleotide phosphodiesterase isozymes and the design of selective inhibitorsTrends in Pharmacological Sciences, 1990
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970