Actions of morphine on the segmental reflex of the decerebrate‐spinal cat
Open Access
- 1 March 1973
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 47 (3) , 457-464
- https://doi.org/10.1111/j.1476-5381.1973.tb08177.x
Abstract
1 The actions of morphine were studied on the segmental reflex of the decerebrate-spinal cat. Morphine decreased arterial blood pressure. 2 Morphine inhibited mono- and polysynaptic reflexes. The influence of morphine on monosynaptic reflexes was more obvious at stimulation of the dorsal root at a frequency of 12·5 Hz than at 05 or 2·5 Hz. 3 The total amount of activity recorded from the ventral root after morphine depended on whether or not the evoked reflex was maximal or submaximal. 4 These actions of morphine were antagonized by naloxone.Keywords
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