Teratogenic potential of blighted potato concentrate in rabbits, hamsters, and miniature swine
- 1 August 1978
- journal article
- research article
- Published by Wiley in Teratology
- Vol. 18 (1) , 55-61
- https://doi.org/10.1002/tera.1420180109
Abstract
Freeze‐dried preparations of potatoes infected with Phytophthora infestans or Alternaria solani were fed to pregnant hamsters, rabbits, and miniature swine. No evidence was observed that these diets or the extracts of respective blights were capable of producing teratologic effects in hamsters. Lesions of neurulation and anencephaly were noticed in rabbits and swine, respectively. The need for further pharmacological and toxicological evaluation in sensitive species is emphasized.This publication has 10 references indexed in Scilit:
- Teratological and toxicological studies of alkaloidal and phenolic compounds from Solanum Tuberosum L.Toxicology and Applied Pharmacology, 1976
- Teratogenicity of the solatium alkaloid solasodine and of ‘Kennebec’ potato sprouts in hamstersBulletin of Environmental Contamination and Toxicology, 1976
- The testing of blighted, aged, and control Russet Burbank potato tuber preparation for ability to produce spina bifida and anencephaly in rats, rabbits, hamsters, and miceAmerican Journal of Potato Research, 1975
- Occurrence of spontaneous hemorrhagic necrosis of the central nervous system in fetal hamstersTeratology, 1975
- Failure of Blighted Russet Burbank Potatoes to Produce Congenital Deformities in RatsExperimental Biology and Medicine, 1974
- Nonteratogenicity in rats of blighted potatoes and compounds contained in themTeratology, 1974
- FAILURE TO INDUCE MALFORMATIONS IN FETAL RATS BY FEEDING BLIGHTED POTATOES TO THEIR MOTHERSThe Lancet, 1973
- Experimental Induction of Foetal Malformation with “Blighted” Potato: a Preliminary ReportNature, 1972
- Neural Tube Closure Defects caused by Cytochalasin ?Nature New Biology, 1972
- Pharmacology of solanineToxicology and Applied Pharmacology, 1971