ACTIVE SUPPRESSION OF INVITRO REACTIVITY OF SPLEEN-CELLS AFTER BCG TREATMENT
- 1 January 1978
- journal article
- research article
- Vol. 34 (3) , 431-437
Abstract
Spleen cells from mice injected i.v. with large doses of BCG respond to PHA [phytohemagglutinin] stimulation less intensely than do normal spleen cells. Nylon wool column purified BCG treated T [thymus-derived] cells also had a low PHA reactivity. Unfractionated spleen cells, adherent cells or T-enriched populations from BCG treated mice, when added to normal T cells, lowered their PHA reactivity. When the same BCG treated cell populations were added to tumor cells in vitro, they inhibited their growth.This publication has 12 references indexed in Scilit:
- [Spleen reactivity after BCG treatement: test and strain dependency of the response].1977
- CYTOSTATIC EFFECT OF SPLEEN-CELLS OF TUMOR-BEARING MICE ON SYNGENEIC TUMOR-CELLS1977
- Macrophage regulation of mitogen-induced blastogenesisCellular Immunology, 1977
- The influence upon mitogenic and cellular immunologic reactive systems in vitro by poly(I:C) and BCG murine interferons induced in vivoCellular Immunology, 1976
- Specific and Nonspecific Antitumor Immunity. II. Macrophage-Mediated Nonspecific Effector Activity Induced by BCG and Similar Agents2JNCI Journal of the National Cancer Institute, 1975
- THE MODIFYING EFFECT OF BCG ON THE IMMUNOLOGICAL INDUCTION OF T CELLSThe Journal of Experimental Medicine, 1974
- Immunopotentiation with BCG. II. Modulation of the Response to Sheep Red Blood Cells2JNCI Journal of the National Cancer Institute, 1973
- A rapid method for the isolation of functional thymus‐derived murine lymphocytesEuropean Journal of Immunology, 1973
- On the Mode of Action of BCGNature New Biology, 1973
- ACTIVE IMMUNOTHERAPY FOR ACUTE LYMPHOBLASTIC LEUKÆMIAThe Lancet, 1969