A Method for the Regiospecific Synthesis of Unsymmetric Acyclic Enones via Enol Boranes
- 1 January 1980
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 10 (9) , 667-674
- https://doi.org/10.1080/00397918008065648
Abstract
Several procedures have been developed for the synthesis of α, β-unsaturated ketones via β-elimination of suitable derivatives (X=sulfoxy1-, selenoxy2,3-, bromo4-). In general, this approach requires position specific enolate formation, and as a result, is intrinsically inapplicable to unsymmetric acyclic substrates, owing to little position selectivity if both αand α′-positions are available for deprotonation.Keywords
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