HUMAN URINARY-EXCRETION PATTERN OF MORPHINE AND CODEINE FOLLOWING CONSUMPTION OF MORPHINE, OPIUM, CODEINE AND HEROIN

1 January 1977

journal article
research article

Vol. 29 (3) , 45-74

Abstract

The ratio of the proportion of codeine to morphine excretion in urine may be used to determine the nature of the drugs consumed. Several factors affect the urinary excretion pattern of morphine alkaloids: detoxification efficiency of metabolism, prevalance of demethylation pathways (which result in conversions), daily fluctuation of metabolic rate and route of drug intake. The observed correlation is useful in effective control and rehabilitation of drug addiction.

This publication has 1 reference indexed in Scilit:

STUDIES ON ENZYMATIC N- + O-DEMETHYLATION OF NARCOTIC ANALGESICS + EVIDENCE FOR FORMATION OF CODEINE FROM MORPHINE IN RATS + DOGS
1964